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CAS No. | 704888-90-4 | Cat. No. | BCP43419 |
Name | ARP100 | ||
Synonyms | ARP-100; ARP 100; | ||
SMILES | CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2 | ||
Chemical Name | |||
Formula | C17H20N2O5S | M. Wt | 364.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1' pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM). |
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