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ARP100 Chemical Structure

ARP100

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43419CAS No. :704888-90-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 704888-90-4 Cat. No. BCP43419
Name ARP100
Synonyms ARP-100; ARP 100;
SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2
Chemical Name
Formula C17H20N2O5S M. Wt 364.42
Purity 98% Storage Store at 4-8°C
Description ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1' pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).
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