LQZ-7I
| CAS No. | 195822-23-2 | Cat. No. | BCP43515 |
| Name | LQZ-7I | ||
| Synonyms | LQZ 7I; LQZ7I; | ||
| Formula | C20H14F2N4 | M. Wt | 348.35 |
| Description | LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Survivin | ||
Structure
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