LQZ-7I New
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| CAS No. | 195822-23-2 | Cat. No. | BCP43515 |
| Name | LQZ-7I | ||
| Synonyms | LQZ 7I; LQZ7I; | ||
| SMILES | C1=CC=C2C(=C1)N=C(C(=N2)NC3=CC=C(C=C3)F)NC4=CC=C(C=C4)F | ||
| Chemical Name | |||
| Formula | C20H14F2N4 | M. Wt | 348.35 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly. | ||
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