Dersimelagon
  • 化学数据
CAS号 1835256-48-8 货号 BCP43656
中文名 Dersimelagon
英文名 Dersimelagon
中文别名
英文别名 MT-7117;
分子式 C36H45F4N3O5 分子量 675.75
  • 用途
生物活性 Dersimelagon is an orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R; melanocyte-stimulating hormone receptor; MSHR; melanin-activating peptide receptor; melanotropin receptor) agonist, that can potentially be used to prevent phototoxicity. Upon administration, dersimelagon targets, binds to and activates MC1R. This may prevent phototoxicity and related pain in erythropoietic protoporphyria (EPP) or X-Linked Protoporphyria (XLP) patients. MC1R, a G protein-coupled receptor that binds to melanocortins and are located on melanocytes, is involved in regulating mammalian skin and hair color.
信号通路 GPCR/G Protein 
靶 点 Melanocortin Receptor 

结构式

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