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| CAS号 | 1835256-48-8 | 货号 | BCP43656 |
| 中文名 | Dersimelagon | ||
| 英文名 | Dersimelagon | ||
| 中文别名 | |||
| 英文别名 | MT-7117; | ||
| SMILES | COCC1CN(CC1C2=C(C=C(C=C2)C(F)(F)F)N3CCC(CC3)C(=O)O)C(=O)C4(CN(CC4C5=CC=C(C=C5)OC)C6CCCC6)F | ||
| 化学名称 | |||
| 分子式 | C36H45F4N3O5 | 分子量 | 675.75 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Dersimelagon is an orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R; melanocyte-stimulating hormone receptor; MSHR; melanin-activating peptide receptor; melanotropin receptor) agonist, that can potentially be used to prevent phototoxicity. Upon administration, dersimelagon targets, binds to and activates MC1R. This may prevent phototoxicity and related pain in erythropoietic protoporphyria (EPP) or X-Linked Protoporphyria (XLP) patients. MC1R, a G protein-coupled receptor that binds to melanocortins and are located on melanocytes, is involved in regulating mammalian skin and hair color. | ||
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