BIT225
| CAS No. | 917909-71-8 | Cat. No. | BCP43946 |
| Name | BIT225 | ||
| Synonyms | BIT-225;BIT 225; | ||
| Formula | C16H15N5O | M. Wt | 293.32 |
| Description | BIT225, a novel acyl-guanidine, is a novel antiviral drug that blocks Vpu ion channel activity and has anti-HIV-1 activity in vitro. The antiviral effect of BIT225 is most pronounced in cells of the myeloid lineage. With infected circulating monocytes and tissue-resident macrophages representing a key cellular reservoir of HIV-1, BIT225 has a potential role in the eradication of the virus from the host. | ||
| Pathways | Microbiology/Virology | ||
| Targets | HIV | ||
Structure
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