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CAS No. | 917909-71-8 | Cat. No. | BCP43946 |
Name | BIT225 | ||
Synonyms | BIT-225;BIT 225; | ||
SMILES | CN1C=C(C=N1)C2=CC=CC3=C2C=CC(=C3)C(=O)N=C(N)N | ||
Chemical Name | |||
Formula | C16H15N5O | M. Wt | 293.32 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BIT225, a novel acyl-guanidine, is a novel antiviral drug that blocks Vpu ion channel activity and has anti-HIV-1 activity in vitro. The antiviral effect of BIT225 is most pronounced in cells of the myeloid lineage. With infected circulating monocytes and tissue-resident macrophages representing a key cellular reservoir of HIV-1, BIT225 has a potential role in the eradication of the virus from the host. |
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