JNJ-38877605
| CAS No. | 943540-74-7 | Cat. No. | BCP44121 |
| Name | JNJ-38877605 | ||
| Synonyms | JNJ 38877618; JNJ38877618;OMO-1; | ||
| Formula | C20H12F2N6 | M. Wt | 374.35 |
| Description | JNJ-38877618 is a potent, highly selective, orally bioavailable Met (c-Met) kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant Met (c-Met) (2 and 3 nM IC50). | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | c Met | ||
Structure
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