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CAS No. | 943540-74-7 | Cat. No. | BCP44121 |
Name | JNJ-38877605 | ||
Synonyms | JNJ 38877618; JNJ38877618;OMO-1; | ||
SMILES | C1=CC2=C(C=CC(=C2)C(C3=NN=C4N3N=C(C=C4)C5=CC=NC=C5)(F)F)N=C1 | ||
Chemical Name | |||
Formula | C20H12F2N6 | M. Wt | 374.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | JNJ-38877618 is a potent, highly selective, orally bioavailable Met (c-Met) kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant Met (c-Met) (2 and 3 nM IC50). |
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