RAD51-IN-17
| CAS No. | 2101739-18-6 | Cat. No. | BCP44339 |
| Name | RAD51-IN-17 | ||
| Synonyms | AFN39186; AFN-39186; AFN 39186; | ||
| Formula | C22H16ClN3O | M. Wt | 373.83 |
| Description | RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | RAD51 | ||
Structure
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