RAD51-IN-17 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2101739-18-6 | Cat. No. | BCP44339 |
| Name | RAD51-IN-17 | ||
| Synonyms | AFN39186; AFN-39186; AFN 39186; | ||
| SMILES | C1=CC=C2C(=C1)C(=O)N(C(=N2)C=CC3=CN=CC=C3)CC4=CC=C(C=C4)Cl | ||
| Chemical Name | |||
| Formula | C22H16ClN3O | M. Wt | 373.83 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines; also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation; a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers. | ||
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