RIPA-56
| CAS No. | 1956370-21-0 | Cat. No. | BCP44340 |
| Name | RIPA-56 | ||
| Synonyms | RIPA56; RIPA 56; | ||
| Formula | C13H19NO2 | M. Wt | 221.3 |
| Description | RIPA-56 is a potent RIP1 inhibitor. RIPA-56 has RIP1 kinase IC50=13 nM; HT-29 Cell EC50 = 28 nM; in vivo PG: t1/2 = 3.1h. RIPA-56 efficiently reduced tumor necrosis factor alpha (TNFα)-induced mortality and multiorgan damage. Compared to known RIP1 inhibitors, RIPA-56 is potent in both human and murine cells, is much more stable in vivo, and is efficacious in animal model studies. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | RIP | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.