BMS-P5 hydrochloride

  • Chemical Properties
CAS No. 1549811-36-0 Cat. No. BCP44953
Name BMS-P5 hydrochloride
Synonyms BMS-P5; BM P5; BMSP5; BMSP-5; BMSP 5; BMS-P5 HCl;
Formula C27H33ClN6O2 M. Wt 509.05
  • Biological Activity
Description BMS-P5 is a Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor with pIC50 values in the range of 5-​7.5. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma.

Structure

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