BMS-P5 hydrochloride New
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CAS No. | 1549811-36-0 | Cat. No. | BCP44953 |
Name | BMS-P5 hydrochloride | ||
Synonyms | BMS-P5; BM P5; BMSP5; BMSP-5; BMSP 5; BMS-P5 HCl; | ||
SMILES | CC1CCC(CN1C(=O)C2=CC3=C(C(=C2)OC)N(C(=N3)C4=CC5=C(N4CC6CC6)N=CC=C5)C)N.Cl | ||
Chemical Name | |||
Formula | C27H33ClN6O2 | M. Wt | 509.05 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS-P5 is a Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor with pIC50 values in the range of 5-7.5. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma. |
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