PF-04802367
| CAS No. | 1962178-27-3 | Cat. No. | BCP44964 |
| Name | PF-04802367 | ||
| Synonyms | PF04802367;PF 04802367;PF367;PF 367;PF-367; | ||
| Formula | C16H16ClN5O3 | M. Wt | 361.78 |
| Description | PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. PF-04802367 shows desirable central nervous system (CNS) properties and potency. PF-04802367 is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3α and GSK-3β) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively[1]. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.