AMG-131
| CAS No. | 315224-26-1 | Cat. No. | BCP45654 |
| Name | AMG-131 | ||
| Synonyms | AMG 131; AMG131; INT-131; INT 131; INT131; T-0903131; T-131; Ibrigampar; | ||
| Formula | C21H12Cl4N2O3S | M. Wt | 514.21 |
| Description | AMG-131, an orally-administered therapy, is expected to lower blood glucose in type II diabetic patients by improving the body’s ability to respond to insulin. T131 is a selective modulator of PPARg (peroxisome proliferator activated receptor gamma), a receptor involved in regulating the body’s ability to respond to insulin. T131 is not structurally related to the thiazolidinedione class of PPARg agonists, which includes Actos and Avandia. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PPAR | ||
Structure
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