AMG-131 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 315224-26-1 | Cat. No. | BCP45654 |
| Name | AMG-131 | ||
| Synonyms | AMG 131; AMG131; INT-131; INT 131; INT131; T-0903131; T-131; Ibrigampar; | ||
| SMILES | C1=CC=C2C(=C1)C=C(C=N2)OC3=C(C=C(C=C3Cl)NS(=O)(=O)C4=C(C=C(C=C4)Cl)Cl)Cl | ||
| Chemical Name | |||
| Formula | C21H12Cl4N2O3S | M. Wt | 514.21 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | AMG-131, an orally-administered therapy, is expected to lower blood glucose in type II diabetic patients by improving the body’s ability to respond to insulin. T131 is a selective modulator of PPARg (peroxisome proliferator activated receptor gamma), a receptor involved in regulating the body’s ability to respond to insulin. T131 is not structurally related to the thiazolidinedione class of PPARg agonists, which includes Actos and Avandia. | ||
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