BMS-262084

  • Chemical Properties
CAS No. 253174-92-4 Cat. No. BCP45717
Name BMS-262084
Synonyms BMS 262084; BMS262084; BDBM50120368; DNC004491;
Formula C18H31N7O5 M. Wt 425.48
  • Biological Activity
Description BMS-262084 is a potent and selective beta-lactam tryptase inhibitor with therapeutic potential for treating asthma. Coadministration of aprotinin, a trypsin inhibitor, increased the oral absorption of BMS-262084 several fold. In vitro, using Caco-2 cells, BMS-262084 appeared to be a P-gp substrate, with an efflux ratio of 14.
Pathways Protease/Metabolic Enzyme 
Targets Factor Xa 

Structure

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