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CAS No. | 253174-92-4 | Cat. No. | BCP45717 |
Name | BMS-262084 | ||
Synonyms | BMS 262084; BMS262084; BDBM50120368; DNC004491; | ||
SMILES | CC(C)(C)NC(=O)N1CCN(CC1)C(=O)N2C(C(C2=O)CCCN=C(N)N)C(=O)O | ||
Chemical Name | |||
Formula | C18H31N7O5 | M. Wt | 425.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS-262084 is a potent and selective beta-lactam tryptase inhibitor with therapeutic potential for treating asthma. Coadministration of aprotinin, a trypsin inhibitor, increased the oral absorption of BMS-262084 several fold. In vitro, using Caco-2 cells, BMS-262084 appeared to be a P-gp substrate, with an efflux ratio of 14. |
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