SR1664
CAS No. | 1338259-05-4 | Cat. No. | BCP45759 |
Name | SR1664 | ||
Synonyms | SR-1664; SR 1664; | ||
Formula | C33H29N3O5 | M. Wt | 547.61 |
Description | SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | PPAR |
Structure
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