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CAS No. | 1338259-05-4 | Cat. No. | BCP45759 |
Name | SR1664 | ||
Synonyms | SR-1664; SR 1664; | ||
SMILES | CC1=C(N(C2=C1C=C(C=C2)C(=O)N[C@@H](C)C3=CC=C(C=C3)[N+](=O)[O-])CC4=CC=C(C=C4)C5=CC=CC=C5C(=O)O)C | ||
Chemical Name | |||
Formula | C33H29N3O5 | M. Wt | 547.61 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPARγ agonist activity. |
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