Darexaban
| CAS No. | 365462-23-3 | Cat. No. | BCP45981 |
| Name | Darexaban | ||
| Synonyms | YM150; YM 150; YM150;Tanexaban; | ||
| Formula | C27H30N4O4 | M. Wt | 474.55 |
| Description | Darexaban, also known as Tanexaban and YM-150, is a direct inhibitor of factor Xa created by Astellas Pharma. Darexaban and darexaban glucuronide selectively and competitively inhibit FXa, suppressing prothrombin activity at the sites of blood clot (thrombus) formation. This leads to a decrease in blood clot formation in a dose dependent manner. Reducing blood clot formation will decrease blood flow blockages, thus possibly lowering the risk of myocardial infarction, unstable angina, venous thrombosis, and ischemic stroke. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Serine Protease Factor Xa | ||
Structure
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