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Darexaban Chemical Structure

Darexaban

Data Sheet For research use only. Not for human use.
Cat. No. :BCP45981CAS No. :365462-23-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 365462-23-3 Cat. No. BCP45981
Name Darexaban
Synonyms YM150; YM 150; YM150;Tanexaban;
SMILES CN1CCCN(CC1)C2=CC=C(C=C2)C(=O)NC3=C(C=CC=C3O)NC(=O)C4=CC=C(C=C4)OC
Chemical Name
Formula C27H30N4O4 M. Wt 474.55
Purity 98% Storage Store at 4-8°C
Description Darexaban, also known as Tanexaban and YM-150, is a direct inhibitor of factor Xa created by Astellas Pharma. Darexaban and darexaban glucuronide selectively and competitively inhibit FXa, suppressing prothrombin activity at the sites of blood clot (thrombus) formation. This leads to a decrease in blood clot formation in a dose dependent manner. Reducing blood clot formation will decrease blood flow blockages, thus possibly lowering the risk of myocardial infarction, unstable angina, venous thrombosis, and ischemic stroke.
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