Ningetinib
| CAS No. | 1394820-69-9 | Cat. No. | BCP46143 |
| Name | Ningetinib | ||
| Synonyms | CT053; CT 053; CT-053; | ||
| Formula | C31H29FN4O5 | M. Wt | 556.58 |
| Description | Ningetinib is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | TAM Receptor c Met VEGFR | ||
Structure
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