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CAS No. | 1394820-69-9 | Cat. No. | BCP46143 |
Name | Ningetinib | ||
Synonyms | CT053; CT 053; CT-053; | ||
SMILES | CC1=C(C(=O)N(N1C)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OCC(C)(C)O)F | ||
Chemical Name | |||
Formula | C31H29FN4O5 | M. Wt | 556.58 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Ningetinib is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity. |
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