SB-747651A dihydrochloride
| CAS No. | 1781882-72-1 | Cat. No. | BCP46273 |
| Name | SB-747651A dihydrochloride | ||
| Synonyms | SB-747651A 2HCl ;SB 747651A dihydrochloride; SB-747651A dihydrochloride; | ||
| Formula | C16H24Cl2N8O | M. Wt | 415.32 |
| Description | SB-747651A dihydrochloride is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay); targets the N-terminal kinase domain. Inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. Blocks IL-10 production in macrophages. | ||
| Related Products | 607372-46-3（SB-747651A） | ||
| Pathways | MAPK Pathway | ||
| Targets | p38 MAPK | ||
Structure
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