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CAS No. | 607372-46-3 | Cat. No. | BCP46274 |
Related Products | 1781882-72-1(SB-747651A dihydrochloride) | ||
Name | SB-747651A | ||
Synonyms | SB 747651A; SB747651A;SB-747651-A; | ||
SMILES | CCN C2=C(C=NC=C2CNC3CCNCC3)N=C1C4=N | ||
Chemical Name | |||
Formula | C16H22N8O | M. Wt | 342.41 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SB-747651A is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay). It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. |
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