MF438
| CAS号 | 921605-87-0 | 货号 | BCP46714 |
| 中文名 | MF438 | ||
| 英文名 | MF438 | ||
| 中文别名 | |||
| 英文别名 | MF-438; MF 438; | ||
| 分子式 | C19H18F3N5OS | 分子量 | 421.44 |
| 生物活性 | MF-438 is a potent and orally bioavailable SCD inhibitor. MF-438 exhibits good pharmacokinetics and metabolic stability, thereby serving as a valuable tool for further understanding the role of SCD inhibition in biological and pharmacological models of diseases related to metabolic disorders. Co-treatment with cisplatin and MF-438 reverts upregulation of CSCs markers, strongly synergizes in the inhibition of 3D spheroids formation and induces CSCs apoptosis. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | SCD | ||
结构式
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