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SCD

结构式 货号 产品名称 CAS号
MF438 结构式
 BCP46714 MF438 921605-87-0
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with IC50 of 2.3 nM for rSCD1.
YTX-465 结构式
 BCP45763 YTX-465 2225824-53-1
YTX-465 is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).
SCD1 inhibitor-3 结构式
 BCP45762 SCD1 inhibitor-3 1282606-48-7
SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor.
DUN41875 结构式
 BCP41022 DUN41875 1295541-87-5
DUN41875 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. DUN41875 can be used for the research of diabetes.
XEN723 结构式
 BCP41701 XEN723 1072803-08-7
XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.
CVT-11127 结构式
 BCP38005 CVT-11127 1018674-83-3
CVT-11127 is an inhibitor of StearoylCoA Desaturase-1 (SCD1).
PluriSln 1 结构式
 BCP07902 PluriSln 1 91396-88-2
PluriSln 1 is an inhibitor of stearoyl-coA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.
Aramchol 结构式
 BCP19722 Aramchol 246529-22-6
Aramchol is a cholesterol solubilizer that prevents gallstone formation in inbred mice. Aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease.
CVT-12012 结构式
 BCP30029 CVT-12012 1018675-35-8
CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM.
SCD1 inhibitor 结构式
 BCP25220 SCD1 Inhibitor 1231243-91-6
SCD1 inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.The compound exhibited robust in vivo activity with dose-dependent desaturation index lowering effects.
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