COH-SR4

  • Chemical Properties
CAS No. 73439-19-7 Cat. No. BCP46777
Name COH-SR4
Synonyms Mitochondria uncoupler SR4;SR4; SR 4; SR-4;
Formula C13H8Cl4N2O M. Wt 350.03
  • Biological Activity
Description COH-SR4 suppresses adipogenesis in 3T3-L1 cells through indirect activation of AMPK and downstream modulation of the Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, which blocks important regulators involved in protein synthesis, cell cycle progression, and expression of key transcription factors and their target adipogenic genes involved in lipid synthesis.
Pathways PI3K/Akt/mTOR Epigenetics 
Targets AMPK 

Structure

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