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CAS No. | 73439-19-7 | Cat. No. | BCP46777 |
Name | COH-SR4 | ||
Synonyms | Mitochondria uncoupler SR4;SR4; SR 4; SR-4; | ||
SMILES | C1=C(C=C(C=C1Cl)Cl)NC(=O)NC2=CC(=CC(=C2)Cl)Cl | ||
Chemical Name | |||
Formula | C13H8Cl4N2O | M. Wt | 350.03 |
Purity | 98% | Storage | Store at 4-8°C |
Description | COH-SR4 suppresses adipogenesis in 3T3-L1 cells through indirect activation of AMPK and downstream modulation of the Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, which blocks important regulators involved in protein synthesis, cell cycle progression, and expression of key transcription factors and their target adipogenic genes involved in lipid synthesis. |
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