CE-224535
| CAS No. | 724424-43-5 | Cat. No. | BCP46785 |
| Name | CE-224535 | ||
| Synonyms | CE 224535; CE224535; CE-224,535; CE 224,535; CE224,535; | ||
| Formula | C22H29ClN4O6 | M. Wt | 480.94 |
| Description | CE-224535 is a P2X7 receptor antagonist potentially for the treatment of rheumatoid arthritis and osteoarthritis. Clinical trials in 2012 showed that CE-224,535 was not efficacious, compared with placebo, for the treatment of RA in patients with an inadequate response to MTX. CE-224,535 demonstrated an acceptable safety and tolerability profile. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | P2 Receptor | ||
Structure
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