CE-224535 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 724424-43-5 | Cat. No. | BCP46785 |
| Name | CE-224535 | ||
| Synonyms | CE 224535; CE224535; CE-224,535; CE 224,535; CE224,535; | ||
| SMILES | COC(N1C(=O)C=NN(C1=O)C2=CC(=C(C=C2)Cl)C(=O)NCC3(CCCCCC3)O)O | ||
| Chemical Name | |||
| Formula | C22H29ClN4O6 | M. Wt | 480.94 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CE-224535 is a P2X7 receptor antagonist potentially for the treatment of rheumatoid arthritis and osteoarthritis. Clinical trials in 2012 showed that CE-224,535 was not efficacious, compared with placebo, for the treatment of RA in patients with an inadequate response to MTX. CE-224,535 demonstrated an acceptable safety and tolerability profile. | ||
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