Asundexian
| CAS No. | 2064121-65-7 | Cat. No. | BCP46980 |
| Name | Asundexian | ||
| Synonyms | BI1265162; BI-1265162; BI 1265162; BAY2433334; BAY 2433334; BAY-2433334; | ||
| Formula | C26H21ClF4N6O4 | M. Wt | 592.94 |
| Description | Asundexian, also known as BAY2433334 and BI1265162, is a blood coagulation factor XIa inhibitor. Asundexian binds directly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. BAY 2433334 is a promising development candidate for once-daily oral anticoagulation; it is being evaluated in phase 2 dose-finding studies in patients at risk of thrombosis. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Factor Xa | ||
Structure
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