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Asundexian Chemical Structure

Asundexian

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46980CAS No. :2064121-65-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2064121-65-7 Cat. No. BCP46980
Name Asundexian
Synonyms BI1265162; BI-1265162; BI 1265162; BAY2433334; BAY 2433334; BAY-2433334;
SMILES CCC(C(=O)NC1=CC(=C(C=C1)C(=O)N)F)N2C=C(C(=CC2=O)C3=C(C=CC(=C3)Cl)N4C=C(N=N4)C(F)(F)F)OC
Chemical Name
Formula C26H21ClF4N6O4 M. Wt 592.94
Purity 98% Storage Store at 4-8°C
Description Asundexian, also known as BAY2433334 and BI1265162, is a blood coagulation factor XIa inhibitor. Asundexian binds directly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. BAY 2433334 is a promising development candidate for once-daily oral anticoagulation; it is being evaluated in phase 2 dose-finding studies in patients at risk of thrombosis.
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