Mupirocin calcium dihydrate

  • Chemical Properties
CAS No. 115074-43-6 Cat. No. BCP47045
Name Mupirocin calcium dihydrate
Synonyms Calcium Mupirocin Dihydrate;
Formula C52H86CaO18.2H2O M. Wt 1075.34
  • Biological Activity
Description Mupirocin calcium dihydrate is an antibiotic and bacterial metabolite. It is bacteriostatic against S. aureus (MIC = 0.05 µg/ml) and active against skin wound clinical isolates of methicillin-resistant S. aureus (MRSA; MICs = 1-4 µg/ml). Mupirocin inhibits MRSA and P. aeruginosa biofilm formation in vitro.4 It inhibits bacterial cell wall isoleucyl-tRNA synthetase, slowing bacterial growth. Topical administration of Mupirocin (2% v/v) reduces the number of wound colony forming units (CFUs) in a mouse model of MRSA skin infection. Lithium mupirocin as been used to study mupirocin resistance in staphylococcus aureus and in mycoplasma susceptibility studies.
Related Products 73346-79-9(Mupirocin lithium) 12650-69-0(Mupirocin)
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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