Mupirocin calcium dihydrate New
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CAS No. | 115074-43-6 | Cat. No. | BCP47045 |
Related Products | 73346-79-9(Mupirocin lithium) 12650-69-0(Mupirocin) | ||
Name | Mupirocin calcium dihydrate | ||
Synonyms | Calcium Mupirocin Dihydrate; | ||
SMILES | CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)[O-])C)C(C)O.CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)[O-])C)C(C)O.O.O.[Ca+2] | ||
Chemical Name | |||
Formula | C52H86CaO18.2H2O | M. Wt | 1075.34 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Mupirocin calcium dihydrate is an antibiotic and bacterial metabolite. It is bacteriostatic against S. aureus (MIC = 0.05 µg/ml) and active against skin wound clinical isolates of methicillin-resistant S. aureus (MRSA; MICs = 1-4 µg/ml). Mupirocin inhibits MRSA and P. aeruginosa biofilm formation in vitro.4 It inhibits bacterial cell wall isoleucyl-tRNA synthetase, slowing bacterial growth. Topical administration of Mupirocin (2% v/v) reduces the number of wound colony forming units (CFUs) in a mouse model of MRSA skin infection. Lithium mupirocin as been used to study mupirocin resistance in staphylococcus aureus and in mycoplasma susceptibility studies. |
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