H7 dihydrochloride
| CAS No. | 108930-17-2 | Cat. No. | BCP47052 |
| Name | H7 dihydrochloride | ||
| Synonyms | H7 2HCl; | ||
| Formula | C14H19Cl2N3O2S | M. Wt | 364.29 |
| Description | H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively). H-7 inhibits cell invasion and metastasis in B16BL6 cancer cells through the PKC/MEK/ERK pathway. It was also shown to inhibit Topo I and II in murine L929 cells and induce apoptosis via PKC inhibition. | ||
| Related Products | 84477-87-2（H7） | ||
| Pathways | Epigenetics | ||
| Targets | PKC | ||
Structure
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