H7 dihydrochloride New
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CAS No. | 108930-17-2 | Cat. No. | BCP47052 |
Related Products | 84477-87-2(H7) | ||
Name | H7 dihydrochloride | ||
Synonyms | H7 2HCl; | ||
SMILES | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl | ||
Chemical Name | |||
Formula | C14H19Cl2N3O2S | M. Wt | 364.29 |
Purity | 98% | Storage | Store at 4-8°C |
Description | H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively). H-7 inhibits cell invasion and metastasis in B16BL6 cancer cells through the PKC/MEK/ERK pathway. It was also shown to inhibit Topo I and II in murine L929 cells and induce apoptosis via PKC inhibition. |
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