STING activator Compound 53

  • Chemical Properties
CAS No. 2259624-71-8 Cat. No. BCP47281
Name STING activator Compound 53
Synonyms C53;STING agonist-12;
Formula C25H19ClF4N2O2 M. Wt 490.88
  • Biological Activity
Description STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Pathways Others Pathway 
Targets STING 

Structure

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