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CAS No. | 2259624-71-8 | Cat. No. | BCP47281 |
Name | STING activator Compound 53 | ||
Synonyms | C53;STING agonist-12; | ||
SMILES | CC1(C2=C(C=C(C=C2)C(=O)NCC3=C(C=C(C=C3F)F)F)N(C1=O)CC4=C(C=CC=C4Cl)F)C | ||
Chemical Name | |||
Formula | C25H19ClF4N2O2 | M. Wt | 490.88 |
Purity | 98% | Storage | Store at 4-8°C |
Description | STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation. |
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