Lisaftoclax
| CAS号 | 2180923-05-9 | 货号 | BCP47569 |
| 中文名 | Lisaftoclax | ||
| 英文名 | Lisaftoclax | ||
| 中文别名 | |||
| 英文别名 | APG-2575;APG2575;APG 2575;Bcl-2/Bcl-xl inhibitor 1; | ||
| 分子式 | C45H48ClN7O8S | 分子量 | 882.42 |
| 生物活性 | Lisaftoclax is an orally bioavailable and selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities. Upon oral administration, lisaftoclax targets, binds to and inhibits the activity of Bcl-2. This restores apoptotic processes in tumor cells. Bcl-2 is overexpressed in many cancers and plays an important role in the negative regulation of apoptosis; its expression is associated with increased drug resistance and tumor cell survival. | ||
| 信号通路 | Apoptosis Pathway | ||
| 靶 点 | Bcl2 | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！