tri-GalNAc COOH
| CAS号 | 1953146-81-0 | 货号 | BCP48074 |
| 中文名 | tri-GalNAc COOH | ||
| 英文名 | tri-GalNAc COOH | ||
| 中文别名 | |||
| 英文别名 | SGN-46810; | ||
| 分子式 | C75H134N10O35 | 分子量 | 1735.93 |
| 生物活性 | Tri-GalNAc COOH is a functionalized asialoglycoprotein receptor ligand for lysosomal targeting chimera (LYTAC) research and development; incorporates an asialoglycoprotein receptor (ASGPR) ligand with PEG linker and carboxylic acid group reactive handle ready for conjugation to a target protein ligand. Upon binding to the ASGPR tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. Tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to liver hepatocytes. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | PROTAC | ||
结构式
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