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CAS号 | 1953146-81-0 | 货号 | BCP48074 |
中文名 | tri-GalNAc COOH | ||
英文名 | tri-GalNAc COOH | ||
中文别名 | |||
英文别名 | SGN-46810; | ||
SMILES | |||
化学名称 | |||
分子式 | C75H134N10O35 | 分子量 | 1735.93 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tri-GalNAc COOH is a functionalized asialoglycoprotein receptor ligand for lysosomal targeting chimera (LYTAC) research and development; incorporates an asialoglycoprotein receptor (ASGPR) ligand with PEG linker and carboxylic acid group reactive handle ready for conjugation to a target protein ligand. Upon binding to the ASGPR tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. Tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to liver hepatocytes. |
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