CAY10462

  • Chemical Properties
CAS No. 502656-68-0 Cat. No. BCP48084
Name CAY10462
Synonyms CAY 10462;CAY-10462;
Formula C17H25N3O.2HCl M. Wt 360.32
  • Biological Activity
Description 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes.
Related Products 769917-29-5(CAY10434)
Pathways Protease/Metabolic Enzyme 
Targets Cytochrome P450 

Structure

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