CAY10462 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 502656-68-0 | Cat. No. | BCP48084 |
| Related Products | 769917-29-5（CAY10434） | ||
| Name | CAY10462 | ||
| Synonyms | CAY 10462;CAY-10462; | ||
| SMILES | CN(C)CCCCCCOC1=CC=C(C=C1)N2C=CN=C2.Cl.Cl | ||
| Chemical Name | |||
| Formula | C17H25N3O.2HCl | M. Wt | 360.32 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. | ||
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