S 14506

  • Chemical Properties
CAS No. 135722-25-7 Cat. No. BCP48184
Name S 14506
Synonyms S-14506;S14506;
Formula C24H26FN3O2 M. Wt 407.48
  • Biological Activity
Description S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity.
Related Products 286369-38-8(S14506 hydrochloride)
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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