S14506 hydrochloride New
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CAS No. | 286369-38-8 | Cat. No. | BCP48185 |
Related Products | 135722-25-7(S 14506) | ||
Name | S14506 hydrochloride | ||
Synonyms | S 14506 HCl; S14506HCl; S14506 HCl; | ||
SMILES | COC1=CC2=C(C=CC=C2N3CCN(CC3)CCNC(=O)C4=CC=C(C=C4)F)C=C1.Cl | ||
Chemical Name | |||
Formula | C24H27ClFN3O2 | M. Wt | 443.95 |
Purity | 98% | Storage | Store at 4-8°C |
Description | S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. |
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