S14506 hydrochloride

  • Chemical Properties
CAS No. 286369-38-8 Cat. No. BCP48185
Name S14506 hydrochloride
Synonyms S 14506 HCl; S14506HCl; S14506 HCl;
Formula C24H27ClFN3O2 M. Wt 443.95
  • Biological Activity
Description S 14506 is a highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). It potentially binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity.
Related Products 135722-25-7(S 14506)
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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