TC-S 7005
| CAS No. | 1082739-92-1 | Cat. No. | BCP48202 |
| Name | TC-S 7005 | ||
| Synonyms | TC S 7005; TCS 7005; TCS-7005; TCS7005; | ||
| Formula | C21H17N3O3 | M. Wt | 359.38 |
| Description | TC-S 7005 is a potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). TC-S 7005 shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). TC-S 7005 induces mitotic arrest and cell death in HCT 116 colorectal cells. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PLK | ||
Structure
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